Cytoprotective Effects of Cell-Permeable Bifunctional Antioxidant Enzyme, GST-TAT-SOD, against Cisplatin-Induced Cell Damage

Figure 4

Annexin V/PI analysis of apoptosis in L-02 cells at 24 h after treatment with 0.7 μg/mL cisplatin. Cells were stained with Annexin V FITC and PI and detected by flow cytometry. The lower right quadrant (Annexin V+ PI−) represents early apoptosis, whereas the upper right quadrant (Annexin V+ PI+) represents late apoptosis. (a) CON, (b) CDDP, (c) GS + CDDP, and (d) GTS + CDDP.

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