The Evaluation of Oxidative Stress Parameters in Serum Patients with Relapsing-Remitting Multiple Sclerosis Treated with II-Line Immunomodulatory Therapy

Table 7

The most important correlations of the selected parameters of oxidative stress in serum for RRMS patients treated with II-line drugs.

Parameter	Age (years)	Disease duration (years)	ARR	EDSS	Gd + MRI lesions (N)	Group
TOS	NS	NS	NS	NS	NS	FG
MDA	NS	NS	NS	NS	NS
LHP	NS	NS	NS	NS	NS
TOS	NS	NS		NS	NS	NT
MDA	NS	NS		NS	NS
LHP	NS	NS		NS	NS
TOS	NS	NS	NS	NS		IFN
MDA	NS	NS	NS	NS
LHP	NS	NS	NS	NS

FG: RRMS patients treated with fingolimod; NT: RRMS patients treated with natalizumab; EDSS: Expanded Disability Status Scale; ARR: annualized relapse rate; LHP: lipid hydroxyperoxides; MDA: malondialdehyde; TOS: total oxidative status; NA: nonapplicable; R: Pearson linear correlation coefficient.