Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice

Figure 10

DNA migration in the lung (a), heart (b), liver (c), kidney (d), spleen (e), and brain (f), 24 h after intratracheal instillation of saline (control) or 0.5 mg/kg cerium oxide nanoparticles (CeO₂ NPs) in mice. Data are mean ± SEM ( in each group). Images illustrating the quantification of the DNA migration by the COMET assay under alkaline conditions in lung (g), heart (h), liver (i), kidney (j), spleen (k), and brain (l) tissues.

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