Research Article
NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
Figure 6
The inflammasome inhibitor and ROS scavenger NAC reduced the inflammasome levels and cell death induced by HG and H/R conditions. The cell viability (a) and the LDH release (b) were assessed. Calcein-AM/PI was used to detect pyroptosis (c). DCFH-DA assay was used to assess cellular ROS production (d). Data are expressed as the mean ± SD. per group. and versus LG + H/R; # and ## versus HG + H/R.
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