Research Article

Metabolic Syndrome Exacerbates the Recognition Memory Impairment and Oxidative-Inflammatory Response in Rats with an Intrahippocampal Injection of Amyloid Beta 1–42

Figure 5

The injection of Aβ1–42 into the hippocampus increases the concentration of proinflammatory cytokines in HCD-fed rats. (a) IL-1β in the temporal cortex. (b) IL-1β in the hippocampus. (c) TNF-α in the temporal cortex. (d) TNF-α in the hippocampus. Metabolic syndrome induced by HCD and injection with Aβ1–42 increase the concentration of IL-1β and TNF-α, in the TCx and hippocampus (a–d). The mean of data ± SE is plotted. Data were analyzed with one-way ANOVA and the posttest Bonferroni test ( and compared with the vehicle group). compared with the MS group versus MS + Aβ1–42 group.