Carnosic Acid, a Natural Diterpene, Attenuates Arsenic-Induced Hepatotoxicity via Reducing Oxidative Stress, MAPK Activation, and Apoptotic Cell Death Pathway

Table 4

Dock score, Emodel value, and interacting residues in molecular docking analysis.

Sl. number	Proteins	Glide scores (Kcal/mol)	Glide Emodel values	Interacting residues in H-bond interaction	Other interactions
1.	Bax	−3.115	−15.341	Arg 37, Leu 122	Cation-π, π-π stacking with Arg 37
2.	Bcl-2	−4.986	−29.586	—	H-bond with H2O
3.	Caspase 9	−3.596	−23.725	Arg 355	π-π stacking, salt bridge with Arg 355
4.	Caspase 3	−4.263	−30.352	Arg 207, Thr 62	—
5.	Caspase 8	−4.060	−19.905	Glu 396, Thr 467	—
6.	IκB	−6.524	−33.382	Asp 103, Leu 21	—
7.	NF-κB	−6.042	−36.121	Arg 416, Leu 472	π-π stacking with Arg 408
8.	JNK	−4.642	−17.079	Asn 114	—
9.	p38	−5.608	−30.359	—	—