Thrombomodulin as a New Marker of Endothelial Dysfunction in Chronic Kidney Disease in Children
Table 1
Basic clinical data and kidney function parameters depending on thrombomodulin concertation in the investigated group of 59 patients.
Parameter
Thrombomodulin
value
<2xULN ()
≥2xULN ()
Age (years)
10.5 (5.0; 16.0)
12.1 (9.1; 15.3)
0.277
Male sex (n)
17 (65.4%)
19 (57.5%)
0.599
Height (z-score)
−0.35 (−1.77; 0.07)
−1.34 (−2.38; −0.27)
0.097
Body mass (z-score)
−0.84 (1.30; 0.11)
−1.06 (−2.55; −0.01)
0.320
BMI (kg/m2)
16.5 (15.8; 18.6)
16.8 (14.9; 20.1)
0.970
BMI (z-score)
−0.62 (−1.11; 0.53)
−0.66 (−1.45; 0.44)
0.903
Creatinine (μmol/l)
110.8 (93.8; 179.3)
403.0 (283.3; 725.3)
<0.001
Cystatin (mg/l)
1.58 (1.25; 2.06)
4.21 (3.05; 5.82)
<0.001
eGFR Filler (ml/min/1.73 m2)
55.2 (38.8; 72.0)
18.4 (12.0; 26.2)
<0.001
Microalbuminuria (mg/l)
18.0 (10,7; 63.0)
99.5 (24.5; 423.0)
0.005
Values presented as median (25th–75th percentile). Mann–Whitney U test. ULN: upper limit of normal; BMI: body mass index; eGFR: estimated glomerular filtration rate.