Research Article

Thrombomodulin as a New Marker of Endothelial Dysfunction in Chronic Kidney Disease in Children

Table 4

24-hour blood pressure values depending on thrombomodulin concentration in the investigated group of 59 patients.

ParameterThrombomodulin value
<2xULN ()≥2xULN ()

24 h SBP (mmHg)113.0 (105.0; 118.0)118.0 (113.0; 126)0.012
24 h DBP (mmHg)65.0 (61.0; 75.0)69.0 (62.0; 78.0)0.063
24 h MAP (mmHg)82.0 (77.0; 88.0)87.0 (78.0; 92.0)0.022
24 h SBP (SD)0.242 (−1.408; 0.746)0.805 (−0.875; 2.337)0.119
24 h DBP (SD)−0.109 (−1.403; 1.375)0.956 (−1.025; 3.511)0.103
24 h MAP (SD)0.309 (−0.858; 1.040)1.472 (−0.646; 3.145)0.076

Values presented as median (25th–75th percentile). Mann–Whitney U test. ULN: upper limit of normal; SBP: systolic blood pressure; DBP: diastolic blood pressure; MAP: mean arterial pressure.