Research Article

Antiulcer Activity and Potential Mechanism of Action of the Leaves of Spondias mombin L.

Table 3

Effect of ethanolic extract of the leaves of Spondias mombin (SmEE) on hematological and biochemical parameters in female mice 14 days after treatment.

ParametersTreatment
Control (0.9% NaCl solution)SmEE (2000 mg/kg)

Hematological parameters
RBC (106/μL)8.87 ± 0.279.32 ± 0.26
Hb (g/dL)15.15 ± 0.4114.99 ± 0.34
Ht (%)43.57 ± 2.2448.00 ± 1.32
MCV (fL)50.33 ± 0.9551.43 ± 0.53
MCH (pg)17.40 ± 0.8716.09 ± 0.28
MCHC (g/dL)32.12 ± 0.1731.20 ± 0.31
RDW (%)12.30 ± 0.2512.76 ± 0.29
Platelets (103/μL)682.80 ± 49.24612.00 ± 33.83
Biochemical parameters
Creatinine (mg/dL)0.18 ± 0.200.28 ± 0.20
ALP (mg/dL)196.60 ± 20.46236.70 ± 29.04
AST (mg/dL)164.00 ± 25.29224.00 ± 31.92
ALT (mg/dL)64.60 ± 3.7172.20 ± 11.11
BUN (mg/dL)53.80 ± 1.5756.57 ± 7.67

RBC: red blood cell; Hb: hemoglobin; Ht: hematocrit; MCV: mean corpuscular volume; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; RDW: red cell distribution width; ALP: alkaline phosphatase; AST: aspartate aminotransferase; ALT: alanine aminotransferase; BUN: blood urea nitrogen. Values represent the mean ± SEM (/group). Student’s t-test for unpaired samples.