Anti-Inflammatory, Immunomodulatory, and Antioxidant Activities of Allicin, Norfloxacin, or Their Combination against Pasteurella multocida Infection in Male New Zealand Rabbits
Table 2
The effect of allicin, norfloxacin, and their combination treatment in Pasteurella multocida type B infection in male white New Zealand rabbits on some biochemical parameters.
Parameter
Groups
Control
Infected
Infection + allicin
Infection + NF
Infection + NF + allicin
Total protein (g/dl)
5.65 ± 0.06a
3.60 ± 0.07c
4.74 ± 0.08b
4.84 ± 0.04b
5.56 ± 0.02a
Albumin (g/dl)
3.99 ± 0.06a
2.50 ± 0.06d
3.33 ± 0.06c
3.28 ± 0.05 c
3.58 ± 0.04b
Globulin (g/dl)
1.72 ± 0.40 b
1.17 ± 0.01e
1.56 ± 0.03c
1.41 ± 0.03d
1.99 ± 0.03a
IgM (mg/dl)
26.00 ± 0.77b
13.80 ± 0.80e
19.60 ± 0.81c
16.6 ± 0.81d
33.80 ± 0.80a
IgG (mg/dl)
424.4 ± 1.47b
348.6 ± 1.17 e
386.6 ± 2.48c
376.8 ± 2.33d
511.6 ± 3.25a
IL-6 (pg/ml)
224.80 ± 1.46d
325.00 ± 2.07a
250.00 ± 0.84b
243.60 ± 1.66c
246.00 ± 2.43cb
TNF-α (pg/ml)
91.20 ± 1.15c
120.60 ± 2.62a
117.80 ± 1.98a
105.20 ± 2.03b
92.40 ± 2.02c
Values are represented as (). Means within the same row carrying different superscripts (a, b, c, d, and e) are significant at . Ig: immunoglobulin; IL: interleukin; NF: norfloxacin; TNF: tumor necrosis factor.