Apoptosis and Mobilization of Lymphocytes to Cardiac Tissue Is Associated with Myocardial Infarction in a Reperfused Porcine Model and Infarct Size in Post-PCI Patients

Figure 2

Lymphocyte and T cell dynamics in swine with induced infarction. Dynamics of lymphocyte and T cell subsets in blood from swine with induced infarction at different time points: preinfarction (0 h), postinfarction and prereperfusion (90 min), and postreperfusion (2 h and 48 h). (a) Lymphocyte cell count. (b) Lymphocyte apoptosis. Number of Annexin V-positive cells selected in the lymphocyte gate. (c) T cells (CD3). (d) B cells (CD1). (e) CD8 cells. (f) CD4 cells. (g) Treg cells (CD4⁺CD25⁺FOXP3⁺). Data are expressed as mean ± SD. versus preinfarction (0 h). SD: standard deviation; Treg: T regulatory cells.

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