Research Article

Emodin, Physcion, and Crude Extract of Rhamnus sphaerosperma var. pubescens Induce Mixed Cell Death, Increase in Oxidative Stress, DNA Damage, and Inhibition of AKT in Cervical and Oral Squamous Carcinoma Cell Lines

Figure 9

Total protein and phosphorylation (Ser-473 residue) levels of AKT. (a) Total AKT and (b) p-Ser-473-AKT for SiHa; (c) total AKT and (d) p-Ser-473-AKT for C33A; (e) total AKT and (f) p-Ser-473-AKT for HSC-3 (g); total AKT and (h) p-Ser-473-AKT for HaCaT. Results are expressed as mean of electrophoretic bands densitometry, corrected for the control of cells treated with DMSO 0.5% (v/v) (CV), of two independent error (), analyzed by one-way ANOVA with Newman–Keuls post-test (statistically significant difference compared to CV: ; ).