Insights on Localized and Systemic Delivery of Redox-Based Therapeutics

Table 4

Clinical studies using vitamin A.

Vitamin A
Route	Results	Reference
Clinical studies
24 mg; Oral	12 weeks of daily oral vitamin A reduced UV-induced skin lesions	[73]
0.4% lotion; Topical	Topical vitamin A application three times a week for 24 weeks reduced aging-related wrinkles	[74]
0.2% lotion; Topical	Topical vitamin A protects skin from IR-generated reactive species	[72]
20 mg; Oral; 0.05% lotion; Topical	Topical vitamin A more effective in treating photoaging than orally administered	[77]