Activating the PGC-1<i>α</i>/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link

<div>Catalpol reduced oxidative stress in AS. 6–8-week-old male LDLr<sup>−/−</sup> mice were administered with a standard diet with catalpol (0 and 100 mg/kg) or HFD with catalpol (0, 100, and 200 mg/kg). 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Error bars depict the standard deviation. HFD: high fat diet.</div>

Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: Activating the PGC-1<i>α</i>/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link 

Figure 2 | Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link 