Guazuma ulmifolia Lam. Decreases Oxidative Stress in Blood Cells and Prevents Doxorubicin-Induced Cardiotoxicity

Figure 5

DOX-induced cytotoxicity in K562 erythroleukemia cells treated with GUEsb (1.56–25 μg·mL⁻¹) for 24, 48, and 72 h. Viability of K562 cells treated with GUEsb and incubated with or without DOX (0.5 μg·mL⁻¹) for (a) 24, (b) 48, and (c) 72 h. The data are expressed as the . Only the cells treated with GUEsb were compared with the control (K562 cells incubated with culture media only), and significant differences were identified when and . The cells treated with DOX + GUEsb were compared with DOX (K562 cells incubated with 0.5 μg·mL⁻¹ DOX). GUEsb = aqueous extract from G. ulmifolia stem bark.

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(b)

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