Research Article

Guazuma ulmifolia Lam. Decreases Oxidative Stress in Blood Cells and Prevents Doxorubicin-Induced Cardiotoxicity

Table 4

Evolution of body mass, food and water consumption, and relative mass of organs of C57Bl/6 mice induced to oxidative stress with DOX.

ParametersControlDOXDOX + GUEsb

Evolution body weight (%)1.0 ± 0.85a−5.0 ± 1.17b−6.6 ± 3.02b
Food intake (g·day−1)37.1 ± 4.7428.1 ± 4.1127.8 ± 3.46
Water intake (mL−1·day)25.9 ± 0.8622.0 ± 1.8521.9 ± 1.67
Heart (g·100−1 of body weight)0.48 ± 0.020.55 ± 0.050.47 ± 0.01
Liver (g·100−1 of body weight)4.36 ± 0.134.94 ± 0.164.87 ± 0.19
Kidney (g·100−1 of body weight)1.08 ± 0.071.05 ± 0.021.02 ± 0.01

The data are expressed as the (). Different letters signify statistical differences at . GUEsb = aqueous extract from G. ulmifolia stem bark.