Research Article

Vildagliptin Attenuates Hepatic Ischemia/Reperfusion Injury via the TLR4/NF-κB Signaling Pathway

Table 1

Effect of hepatic ischemia/reperfusion (HIR) alone or in combination with intraperitoneal administration of vildagliptin (Vilda) (10 mg/kg for 10 days) on serum alanine transaminase (ALT) and aspartate transaminase (AST) levels in experimental rats. All data were expressed as mean ± SD.

GroupALT (U/L)AST (U/L)

Sham23.52 ± 1.1247.26 ± 4.6
HIR86.06 ± 4.71116.6 ± 8.7
Vilda + HIR37 ± 5.2465 ± 4.3

aSignificant difference from the sham group at . bSignificant difference from the HIR group at .