Research Article

Vildagliptin Attenuates Hepatic Ischemia/Reperfusion Injury via the TLR4/NF-κB Signaling Pathway

Table 3

Comparison of histopathological scores between Sham, HIR, and Vilda + HIR groups (%).

ParametersShamHIRVilda + HIR

Sinusoidal congestion
 Score 010 (100%)0 (0%)6 (60%)37.5<0.001
 Score 10 (0%)0 (0%)4 (40%)
 Score 30 (0%)2 (20.0%)0 (0%)
 Score 40 (0%)4 (40%)0 (0%)
 Score 50 (0%)4 (40%)0 (0%)
Hemorrhage
 Score 010 (100%)2 (20%)10 (100%)21.8<0.05
 Score 10 (0%)4 (40%)0 (0%)
 Score 20 (0%)2 (20%)0 (0%)
 Score 30 (0%)2 (20%)0 (0%)
Hepatocyte degeneration
 Score 010 (100%)0 (0%)0 (0%)43.0<0.001
 Score 10 (0%)0 (0%)2 (20%)
 Score 20 (0%)0 (0%)2 (20%)
 Score 30 (0%)0 (0%)2 (20%)
 Score 40 (0%)4 (40%)2 (20%)
 Score 50 (0%)6 (60%)2 (20%)
Parenchymal necrosis
 Score 010 (100%)0 (0%)10 (100%)30<0.001
 Score 40 (0%)4 (40%)0 (0%)
 Score 50 (0%)6 (60%)0 (0%)