Dysfunction of Nrf2-ARE Signaling Pathway: Potential Pathogenesis in the Development of Neurocognitive Impairment in Patients with Moderate to Severe Obstructive Sleep Apnea-Hypopnea Syndrome

Table 11

The correlation between Nrf2, HO-1 mRNA, protein expression, and neurocognitive function in the OSAHS group.

	Nrf2 mRNA	Total Nrf2 protein	Nuclear Nrf2 protein	HO-1 protein
HVLT-R		−0.557	0.460	0.243
		0.025	0.073	0.364
WMS-III: spatial span		−0.365	0.155	0.383
		0.165	0.567	0.143
NAB: mazes		−0.680	0.525	0.568
		0.004	0.037	0.022

Data are presented as partial correlation coefficients (r) and p values. Partial correlation analysis (adjusted covariates: age, education, sex, BMI, and smoking index. and . HVLT-R, Hopkins Verbal Learning Test-Revised; WMS-III: spatial span, Wechsler Memory Scale-III: spatial span; NAB: mazes, Neurological Assessment Battery: mazes.