Inhibitory Effects of Momordicine I on High-Glucose-Induced Cell Proliferation and Collagen Synthesis in Rat Cardiac Fibroblasts

Figure 6

Schematic illustration of the proposed mechanism for high-glucose-induced rat cardiac fibroblast activation and momordicine I-inhibited fibrogenesis through the Nrf2-mediated inhibition of oxidative stress and TGF-β1 signaling.