Research Article

Oxidative Stress-Mediated Overexpression of Uracil DNA Glycosylase in Leishmania donovani Confers Tolerance against Antileishmanial Drugs

Table 1

Comparison of kinetic parameter of recombinant UNG of leishmania with that of plasmodium and human.

SubstrateKm (μM)
LdUNGPfUDGhUNG

47-mer-SS-U1.24 ± 0.91.632.2 ± 0.2

Suksangpleng et al. [26].