Research Article
A Positive Feedback Loop of Profilin-1 and RhoA/ROCK1 Promotes Endothelial Dysfunction and Oxidative Stress
Figure 1
Effects of AGEs on HUVECs and profilin-1 expression for (a) intracellular ROS, (b) apoptosis, (c) tube formation, and (d) migratory abilities were measured in HUVECs treated with 200 μg/ml AGEs for 24 h. (e) Western blotting for profilin-1 in HUVECs after AGE treatment for 24 h. β-actin serves as a loading control. .
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