2-Methoxyestradiol Attenuates Testosterone-Induced Benign Prostate Hyperplasia in Rats through Inhibition of HIF-1α/TGF-β/Smad2 Axis

Figure 4

Effect of 2ME on prostate content of IL-1β (a), TNF-α (b), NF-κB (c), and TGF-β (d) in testosterone-treated rats. Data are expressed as mean ± SD (). a or b: statistically significant from control or testosterone group, respectively, at using one-way ANOVA followed by Tukey’s post hoc test.

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