The Electrical Stimulation of the Bed Nucleus of the Stria Terminalis Causes Oxidative Stress in Skeletal Muscle of Rats

Figure 8

The potential consequences of reaction to the long-term “psychological stress” lead to the free radical damage of skeletal muscle. (1) The bed nucleus of the stria terminalis is linked with the chronic stress response. (2) The chronic BST stimulation induces massive plasma CORT secretion by HPA axis. (3) The chronic stress response evokes ROS generation in two types of skeletal muscles. (4) Lipid and protein peroxidation in muscle is associated with higher CORT level. (5) The activity of antioxidant enzymes is elevated during the chronic stress response.