Intravenous Anesthetic Protects Hepatocyte from Reactive Oxygen Species-Induced Cellular Apoptosis during Liver Transplantation In Vivo
Table 1
Histological score of liver injury by OALT.
Groups
Centrilobular cell death
Ballooning
Inflammation
Grade
Average
Grade
Average
Grade
Average
+3
+2
+1
0
+3
+2
+1
0
+3
+2
+1
0
Sham
0
0
0
8 (100)
0
0
0
0
8 (100)
0
0
0
0
8 (100)
0
OALT
2 (25)
3 (38)
3 (38)
0 (0)
1.9#
3 (38)
3 (38)
2 (25)
0 (0)
2.1#
5 (63)
2 (25)
1 (13)
0 (0)
2.5#
OALT + INT
2 (25)
4 (50)
2 (25)
0 (0)
2.0#
2 (25)
4 (50)
2 (25)
0 (0)
2.0#
4 (50)
3 (38)
1 (13)
0 (0)
2.4#
OALT + HPro
0 (0)
1 (13)
6 (75)
1 (13)
1.0
0 (0)
1 (13)
7 (88)
0 (0)
1.1
0 (0)
2 (25)
5 (63)
1 (13)
1.1
OALT + LPro
0 (0)
1 (13)
7 (88)
0 (0)
1.1
0 (0)
2 (25)
6 (75)
0 (0)
1.3
0 (0)
4 (50)
4 (50)
0 (0)
1.5
OALT + VAS
0 (0)
2 (25)
6 (75)
0 (0)
1.3
0 (0)
2 (25)
5 (63)
1 (13)
1.1
0 (0)
3 (38)
4 (50)
1 (13)
1.3
Numbers of rats are shown, with percentages enclosed within parenthesis. Grade indication: no change (0), mild (1), moderate (2), and severe (3). vs. the sham group, vs. the OALT group, and vs. the OALT group.
