Research Article
Disruption of the Circadian Clock Alters Antioxidative Defense via the SIRT1-BMAL1 Pathway in 6-OHDA-Induced Models of Parkinson’s Disease
Figure 4
Acetylated BMAL1 was elevated, and SIRT1 was decreased in 6-OHDA-treated rats and SH-SY5Y cells. (a) Expression of BMAL1, acetylated BMAL1, and SIRT1 in the striatum of 6-OHDA-lesioned rats. (b) Expression of BMAL1, acetylated BMAL1, and SIRT1 in 6-OHDA-treated SH-SY5Y cells. versus the control group.
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