Transcriptome Remodeling of Differentiated Cells during Chronological Ageing of Yeast Colonies: New Insights into Metabolic Differentiation

Figure 3

Comparing cell subpopulations in 6-day-old colonies. UpSet plot of datasets of DE genes in upper (U6), lower (L6), and marginal (M6) cells from 6-day-old colonies (upper part). Horizontal black bar chart indicates numbers of genes, DE in each individual comparison. Intersect “connectors” indicate comparisons in which a given number of genes (vertical blue bar chart) were DE. Only major intersections are shown. Heat map of genes assigned to functional categories and clustered according to FC and DE in different sample comparisons (lower part). Number in heat map cell = number of genes from FC, up- or downregulated in sample comparison. The higher the number of up-/downregulated genes, the more intense the color. Arrows indicate upregulation/downregulation in the respective subpopulation ratio(s); asterisk indicates categories of genes that are differently up-/downregulated in the respective subpopulation ratios.