Transcriptome Remodeling of Differentiated Cells during Chronological Ageing of Yeast Colonies: New Insights into Metabolic Differentiation

Figure 8

Comparing small lower-cell subpopulations. UpSet plot of datasets of DE genes in small lower-cell subpopulations (L1 and L2) and upper (U15) and lower (L15) cells from 15-day-old colonies (upper part). Only major intersections are shown. Heat map of genes assigned to functional categories and clustered according to FC and DE in different sample comparisons (lower part). Number in heat map cell = number of genes from FC, up- or downregulated in sample comparison. The higher the number of up-/downregulated genes, the more intense the color. Arrows indicate upregulation/downregulation in the respective subpopulation ratio(s); asterisk indicates the category of genes that are differently up-/downregulated in the respective subpopulation ratios.