Di-2-pyridylhydrazone Dithiocarbamate Butyric Acid Ester Exerted Its Proliferative Inhibition against Gastric Cell via ROS-Mediated Apoptosis and Autophagy

Figure 1

The chemical structure and growth inhibition of DpdtbA. The effect of DpdtbA on morphology. SGC-7901 cells: (a) control and (b) 5 μM DpdtbA after 16 h treatment. MGC-803 cells: (c) control and (d) 5 μM DpdtbA treatment after 16 h treatment. (e) Structure of DpdtbA. (f) Proliferation inhibition of DpdtbA against SGC-7901 cell line (IC₅₀ = 4.2 ± 0.52 μM). (g) Proliferation inhibition of DpdtbA against MGC-803 cell line (IC₅₀ = 3.8 ± 0.4 μM).

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