Research Article

Antihypertensive Effect of Ethanolic Extract from Acanthopanax sessiliflorus Fruits and Quality Control of Active Compounds

Figure 9

Effects of DHP1501 on blood pressure; SBP and DBP. (a) Changes in SBP and DBP induced by DHP1501 for 4 weeks. (b) Changes in SBP and DBP induced by DHP1501 at the end of the experiment period. Groups included the following: WKYs as normal control; SHR (saline as the vehicle); SHR-captopril 100 (a 4-week daily course of oral captopril at a dose of 100 mg/kg); SHR-DHP1501 200 (a 4-week daily course of oral DHP1501 at a dose of 200 mg/kg); SHR-DHP1501 400 (a 4-week daily course of oral DHP1501 at a dose of 400 mg/kg); and SHR-DHP1501 600 (a 4-week daily course of oral DHP1501 at a dose of 600 mg/kg). (c) Effect of DHP1501 on SBP and DBP measured by an invasive method. Values were expressed as the mean ± SD (/group) (, versus the WKY group; , versus the SHR group).
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