Methionine Sulfoxide Reductase B1 Regulates Hepatocellular Carcinoma Cell Proliferation and Invasion via the Mitogen-Activated Protein Kinase Pathway and Epithelial-Mesenchymal Transition

Table 2

The relationship between MsrB1 expression levels and clinicopathological characteristics.

MsrB1 density
Variable	High	Low	value
In general
Tumor tissue	80	32
Sex
Male	59	25	0.3
Female	14	3
Age (years)
≤50	22	15	0.028
>50	51	13
Tumor size (cm)
≤3	30	6	0.04
>3	45	25
AFP (ng/ml)
≤400	40	13	0.4251
>400	30	14
HBsAg
Positive	70	25	0.619
Negative	10	7
Liver cirrhosis
Yes	67	16	0.04
No	20	12
BCLC
0-B	77	27	0.03
C	1	3
TNM stage (AJCC)
I-II	72	29	0.96
III-IV	8	3

MsrB1 expression levels were related to age (), tumor size (), liver cirrhosis (), and BCLC stage ().