Table 3: Clinical markers, thrombotic risk, and platelet activation.

High T0High T4Low T0Low T4

Glucose mg/dl90.3 ± 5.594.0 ± 7.489.6 ± 4.390.6 ± 6.8
Insulin μUI/ml8.1 (5.4–11.8)8.1 (5.0–9.4)6.8 (5.0–9.4)7.9 (5.3–10.5)
HOMA-IR1.7 (1.1-2.6)1.8 (1.1-2.1)1.4 (1.0-1.9)1.6 (1.1-2.3)
TC mg/dl217.1 ± 35.8217.3 ± 38.3207.9 ± 41.0204.8 ± 40.3
LDL mg/dl140.1 ± 27.0137.7 ± 28.9127.9 ± 35.1125.4 ± 33.7
HDL mg/dl58.9 ± 8.160.5 ± 7.758.3 ± 8.557.3 ± 9.3
TG mg/dl88 (65–104)86 (73–100)110 (64–161)84 (69–176)
BR mg/dl0.5 (0.4–0.6)0.5 (0.4–0.7)0.6 (0.3–0.7)0.5 (0.3–0.6)
dir-BR mg/dl0.12 (0.11–0.15)0.12 (0.11–0.16)0.14 (0.09–0.17)0.13 (0.10–0.16)
ind-BR mg/dl0.38 (0.29–0.49)0.38 (0.31–0.54)0.45 (0.21–0.55)0.37 (0.23–0.47)
Proteins g/dl6.8 ± 0.36.9 ± 0.16.8 ± 0.57.0 ± 0.4
Fibrinogen mg/dl336.9 ± 39.7340.9 ± 43.9319.3 ± 43.3325.2 ± 46.9
D-dimer ng/ml323.7 (251.6–412.3)288.5 (234.7–397.6)277.3 (213.5–427.9)320.2 (228.1–414.3)
Pt 10^3/microL262 (223–288)244 (212–293)248 (219–301)245 (220–336)
MPV fL8.6 ± 0.98.6 ± 0.98.5 ± 0.78.4 ± 0.7
PDW %16.3 ± 0.416.3 ± 0.416.3 ± 0.516.4 ± 0.5
PAC-1 R1140.5 (49.1–226.3)156.2 (135.7–187.8)122.6 (98.5–255.1)199.8 (151.1–291.1)
PAC-1 R1 AA159.4 (48.8–174.4)155.7 (147.1–212.7)151.8 (62.9–193.2)206.2 (129.9–256.0)
PAC-1 R2234.2 (34.9–373.7)138.2 (99.8–187.5)277.5 (68.2–411.8)260.1 (183.1–296.8)
PAC-1 R2 AA213.8 ± 150.7132.5 ± 78.3215.6 ± 124.2169.0 ± 98.9

Values at baseline (high T0 and low T0) and 4 weeks after high (4200 g/week) or low (800 g/week) vegetable consumption. Data are expressed as mean ± SD (normality test passed; ANOVA applied) or median (25%, 75%) (normality test failed; Kruskal-Wallis ANOVA on ranks applied). Pt: platelets; MPV: mean platelet volume; PDW: platelet distribution width; PAC-1 expression was measured after ex-vivo platelets’ activation (AA: arachidonic acid; R1 and R2 gates are depicted in Figure 2); TC: total cholesterol; TG: triglycerides; UA: uric acid.