Modulation of Oxidative Status by Normoxia and Hypoxia on Cultures of Human Dermal Fibroblasts: How Does It Affect Cell Aging?

<div>Levels of coenzyme Q<sub>10</sub> in HDF analyzed by HPLC. HDF were serially passaged under the two oxygen tensions (21% and 5%), and at matched cell passage, intracellular CoQ<sub>10</sub> was analyzed at various stages of cellular aging—young (Y) and old (O) HDF. Total CoQ<sub>10</sub> levels (a) and % of oxidized CoQ<sub>10</sub> (b) in HDF. 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Oxidative Medicine and Cellular Longevity

fig5

Figure 5

Figure 5: Modulation of Oxidative Status by Normoxia and Hypoxia on Cultures of Human Dermal Fibroblasts: How Does It Affect Cell Aging? 