Antiskin Inflammatory Activity of Black Ginger (Kaempferia parviflora) through Antioxidative Activity

Figure 2

Inhibitory effect of Kaempferia parviflora extract (KPE) on sUV-induced prostaglandin E2 (PGE2) production via COX-2 reduction in JB6 P⁺ and HaCaT cells. (a) The cytotoxicity of KPE was measured using MTS analysis as indicated in Materials and Methods. The COX-2 expression and PGE2 production were determined with Western blot analysis and PGE2 assay in JB6 P⁺ (b, c) and HaCaT (d). KPE was pretreated to the cells for 1 h before sUV (23 kJ/cm²) exposure. After 3 h, the protein was collected. The pound signs (##) and asterisks () indicate significant difference () compared to the untreated group and sUV-treated group, respectively. And the asterisk () represents a significant difference () compared to the sUV-treated group.

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