Research Article
Isopropyl Caffeate: A Caffeic Acid Derivative—Antioxidant Potential and Toxicity
Table 5
Effects of acute isopropyl caffeate treatment on biochemical parameters of female mice.
| Groups | Dose (mg/kg) | AST (U/I) | ALT (U/I) | Alkaline phosphatase (U/I) | Serum creatinine (mg/dl) | Urea (mg/dl) | Glucose (mg/dl) | Cholesterol (mg/dl) |
| Control | — | 322.4 ± 12.69 | 144.5 ± 12.55 | 116.2 ± 4.09 | 0.31 ± 0.02 | 44.00 ± 2.26 | 188.3 ± 5.58 | 91.00 ± 2.89 | Treated | 300 | 177.2 ± 17.58 | 62.00 ± 5.90 | 125.5 ± 9.19 | 0.36 ± 0.01 | 34.40 ± 2.38 | 201.5 ± 9.35 | 88.83 ± 3.29 | Treated | 2000 | 166.5 ± 20.90 | 55.25 ± 4.05 | 103.3 ± 11.79 | 0.31 ± 0.01 | 42.67 ± 2.33 | 188.3 ± 11.78 | 97.33 ± 5.49 |
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The results are expressed as mean ± SD analysis by ANOVA followed by post-Dunnett’s test, (control and dose of 300 mg/kg of 2000 mg/kg ). |