|
References | Nanoparticle studied | Function | Cell type |
|
Manickam et al. [112] | Iron oxide nanoparticles | Oxidant by Nox 4 overexpression | Myocardium from mice |
Petty [117] | WO3-Pt nanoparticles | Oxidant. NADPH oxidase biomimetic | Tumor cells |
Sun et al. [113] | Silver nanoparticles | Oxidant by increasing Nox 4 expression | Human umbilical vein endothelial cells |
Ramirez-Lee et al. [131] | Silver nanoparticles | Increase of hypertension due to a decrease in NO levels | Myocardium from rats |
T. Yu et al. [142] | PLGA nanoparticles | Carrier. Treatment for hypertension | Hypertensive rats |
Le et al. [132] | PLGA nanoparticles | ROS scavenger at vascular level and endothelial protector | Human umbilical vascular endothelial cells |
Reddy and Labhasetwar [63] | PLGA nanoparticles | SOD carrier | Rat focal cerebral ischemia/reperfusion injury |
Hennig et al. [141] | PEGylated quantum dots | Carrier of angiotensin II | AT1R-expressing cells |
C. Guo et al. [158] | Silica nanoparticles | Endothelial injury induced by mitochondrial dysfunction | Human endothelial cells |
Farooq et al. [157] | Silica nanoparticles | Endothelial dysfunction induced by oxidative stress | Aorta from rat |
D. Lee et al. [71] | PVAX | Antioxidant, anti-inflammatory, and antiapoptotic activity | Hind-limb and liver from an ischemia/reperfusion model in mice |
Marrache and Dhar [80] | PLGA-b-PEG-TPP nanoparticles | Nanocarriers | Mitochondria-acting therapeutics |
Marushima et al. [73] | RNP | Neuroprotective agent due to its ability to scavenge free radicals | Middle cerebral artery from rats with cerebral ischemia/reperfusion injury |
Chonpathompikunlert et al. [74] | Redox-polymer nanotherapeutics | Treatment of the neurodegenerative diseases | Brain from SAMP8 mice |
Ciofani et al. [60] | Nanoceria | SOD and catalase mimetic | PC12 neuronal-like cells |
Estevez et al. [69] | Nanoceria | Reduction of oxidative and nitrosative damage after stroke | Mouse hippocampal brain slice model of ischemia |
Hirst et al. [67] | Nanoceria | Anti-inflammatory and NO scavenger | Murine macrophages |
Niu et al. [152] | Nanoceria | Antioxidant | Cultured rat H9c2 cardiomyocytes |
Niu et al. [161] | Nanoceria | Antioxidant and anti-inflammatory | Murine myocardium |
Gojova et al. [164] | Nanoceria | Inflammatory effect | Human aortic endothelial cells |
Wingard et al. [162] | Nanoceria | Vascular dysfunction | Aorta from mice |
Minarchick et al. [159] | Nanoceria | Vascular antioxidant | Arterioles from hypertensive rats |
Minarchick et al. [163] | Nanoceria | Prooxidant. Microvascular dysfunction | Arteriola from rats |
Kennedy et al. [165] | Iron oxide, yttrium oxide, cerium oxide, zinc oxide | Proinflammatory | Human vascular endothelial cell line |
Park et al. [187] | Nanoparticles based on polyoxalate | Antioxidant and anti-inflammatory | Doxorubicin-treated mice heart |
Seshadri et al. [189] | Polyketal particles | SOD carrier | Rat myocardium |
|