The Role of Oxidative Stress, Selected Metals, and Parameters of the Immune System in Male Fertility

Table 3

The levels or activity of malondialdehyde (MDA), lipofuscin, total oxidant status (TOS), superoxide dismutase (SOD), Mn-SOD, CuZn-SOD, thiol groups, catalase (CAT), glutathione reductase (GR), glutathione peroxidase (GPx), glutathione-S-transferase (GST), glucose-6-phosphate dehydrogenase (G6PD), total antioxidant capacity (TAC), and α-tocopherol in the study population (group ME: mediocre semen morphology and group EX: excellent semen morphology). value—comparison between the ME and EX groups using Student’s t-test.

	ME group		EX group		value	Relative change
	Mean	SD	Mean	SD	Mean	SD
MDA concentration (μmol/l)	2.32	0.81	2.51	1.13	0.474	8%
Lipofuscin concentration (RF)	3.81	1.50	4.02	1.65	0.975	5%
TOS (μmol/l)	11.00	14.23	11.0	13.7	0.697	0%
SOD activity (NU/mg protein)	4.09	1.59	4.62	1.50	0.059	13%
Mn-SOD activity (NU/mg protein)	0.83	1.06	0.88	0.93	0.358	6%
CuZn-SOD activity (NU/mg protein)	3.12	1.46	3.55	1.30	0.050	14%
Thiol group concentration (μmol/g protein)	4.73	2.46	5.43	2.70	0.098	15%
CAT activity (U/g protein)	11.9	7.73	19.3	20.6	0.030	63%
GR activity (U/g protein)	1.64	1.58	1.85	2.09	0.668	13%
GPx activity (U/g protein)	3.13	4.71	1.62	2.91	0.273	−48%
GST activity (mU/g protein)	83.3	60.9	84.8	55.1	0.732	2%
G6PD activity (U/g protein)	1.22	1.09	1.70	1.23	0.049	39%
TAC (mmol/l)	1.38	0.27	1.29	0.22	0.199	−7%
α-Tocopherol concentration (μg/ml)	10.60	3.82	7.18	3.78	<0.001	−32%

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