The Role of TLR4 on PGC-1α-Mediated Oxidative Stress in Tubular Cell in Diabetic Kidney Disease

Table 2

Physical and metabolic parameters in mice.

	db/m	db/db	db/db + TAK242
Body weight (g)	35.9 ± 0.52	64.00 ± 5.02	58.42 ± 1.54
Blood urea nitrogen (mmol/L)	5.59 ± 0.36	11.42 ± 0.88	7.04 ± 0.38
Serum creatinine (μmol/L)	3.76 ± 0.19	16.77 ± 0.92	8.91 ± 0.35
Urine protein (mg/24 h)	7.53 ± 0.35	26.30 ± 1.15	15.31 ± 0.66
ACR (μg/mg Cr)	0.23 ± 0.01	2.89 ± 0.07	2.76 ± 0.08

Values are ; , compared with the db/m group; , compared with the db/db group; urinary albumin : creatinine ratio (ACR).