Protective Effects of Miswak (Salvadora persica) against Experimentally Induced Gastric Ulcers in Rats

Table 4

Oxidative stress and antioxidative profile in ethanol-induced gastric ulcer rat model pretreated with S. persica extract.

	MDA (nmol/g)	GSH (μmol/g)	T.SOD (U/g)	CAT (U/g)	GPX (U/g)	GST (U/g)
Control	101.3 ± 8.2	16.8 ± 1.6	75.4 ± 7.8	11.2 ± 2.6	46.9 ± 7.6	143.2 ± 12.4
EtOH	111.5 ± 7.6	14.2 ± 1.4	70.5 ± 5.4	9.8 ± 1.1	41.7 ± 8.9	131.8 ± 15.8
EtOH + SP200	83.7 ± 8.9	18.6 ± 2.1	85.4 ± 7.1	13.6 ± 2.3	63.8 ± 8.7	165.7 ± 13.3
EtOH + SP400	74.3 ± 9.1	22.9 ± 1.9	96.8 ± 6.4	16.7 ± 2.2	72.9 ± 6.3	181.2 ± 11.8

Values are expressed as mean ± SEM. The means within the same column carrying different superscript letters are significantly different at as determined with one-way ANOVA, followed by Duncan’s post hoc test multiple comparisons. EtOH: ethanol-induced gastric ulcer group; EtOH + SP200: ethanol-induced gastric ulcer pretreated with S. persica extract at a dose of 200 mg/kg b.w.; EtOH + SP400: ethanol-induced gastric ulcer pretreated with S. persica extract at a dose of 400 mg/kg b.w.