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Oxidative Medicine and Cellular Longevity
Volume 2018, Article ID 6712407, 7 pages
Research Article

The Effects of Buckwheat Leaf and Flower Extracts on Antioxidant Status in Mouse Organs

1Neuroscience Institute, Lithuanian University of Health Sciences, Kaunas, Lithuania
2Department of Biochemistry, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania
3Department of Prosthodontics, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania

Correspondence should be addressed to Ilona Sadauskiene; tl.inumsl@eneiksuadas.anoli

Received 13 March 2018; Revised 7 May 2018; Accepted 23 May 2018; Published 14 June 2018

Academic Editor: Demetrios Kouretas

Copyright © 2018 Ilona Sadauskiene et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This study was undertaken to investigate the effects of the extracts of buckwheat leaf and flower on the antioxidant status of the brain and liver tissue. The administration of buckwheat extracts (both concentrations were 10%) to mice (at the dose 10 mL/kg of body weight) for 21 days significantly decreased superoxide dismutase (SOD) activity and reduced the amount of glutathione (GSH) and malondialdehyde (MDA) in the mouse brain, while catalase (CAT) activity significantly increased. In the mouse liver, the amount of GSH and activity of SOD increased, while the CAT activity after administering buckwheat leaf and flower extracts was lower in experimental mice than in the control group. However, the administration of 10% ethanol (for 21 days) to control animals also had a significant effect on the antioxidant system in brain and liver cells. Experimental animals demonstrated rather marked changes in the activities of the antioxidant enzymes SOD and CAT in their liver and brain cells, and changes in the levels of GSH and MDA were observed when compared with the control group.