Hydrogen Sulfide Attenuates LPS-Induced Acute Kidney Injury by Inhibiting Inflammation and Oxidative Stress

Figure 2

H₂S levels decreased in mice with LPS-induced AKI, exogenous H₂S could attenuate renal dysfunction. (a) H₂S levels in plasma. (b) H₂S levels in the kidney tissues. (c) 3-MST activity in the kidney tissues. (d) CBS&CSE activity in the kidney tissues. (e) Representative Western blots for 3-MST, CBS, and CSE expression in the kidney tissues. β-Actin was used as the internal control. (f−h) The quantitative analysis for 3-MST, CBS, and CSE expression in the kidney tissues. (i) Cre levels in plasma. (g) BUN levels in plasma. (k) Representative HE-stained right kidney sections (scale bar = 250 μm). (l) Kidney tubular injury score of three groups.

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