Treatment of NASH with Antioxidant Therapy: Beneficial Effect of Red Cabbage on Type 2 Diabetic Rats

Table 1

Anthropomorphic and metabolic characteristics of rats after 4 months of the administration of different diets.

Variables	ND	HFHF	HFHF/ND	HFHF/NDRC	HFHF/HFHFRC
Physiological variables
Weight gain from 2 to 4 months (g)	63.4 ± 6.9	97.5 ± 4.60	13 ± 12.14^$$$	15.67 ± 12.77^$$$	64.58 ± 6.7^$
Final body weight (g)	558 ± 15.3	628 ± 12.6	570 ± 13.4^$$	533 ± 19.8^$$$	574.25 ± 10.43^$
Body mass index (BMI; g/cm^2)	0.78 ± 0.003	0.86 ± 0.02	0.76 ± 0.02^$$	0.77 ± 0.01^$	0.83 ± 0.03
Abdominal circumference (cm)	22.14 ± 0.59	24.9 ± 0.78	22.08 ± 1.34^$	22.50 ± 0.87^$	23.08 ± 0.61
Abdominal fat (g); (% vs. total weight)	12.22 ± 1.74; 2.17 ± 0.27	34.60 ± 1.38; 4.37 ± 0.96	18.33 ± 3.39^$$$; 3.17 ± 0.49^$$$	15.38 ± 2.81^$$$; 2.84 ± 0.45^$$$	21.65 ± 3.01^$$; 2.55 ± 0.90^$$
Plasmatic metabolic variables
Fasting blood glucose (g/L)	1.10 ± 0.04	1.34 ± 0.04	1.24 ± 0.02^$	1.21 ± 0.3^$$	1.28 ± 0.04
Area under the curve during IpGTT	244.5 ± 18.3	343.2 ± 29.3	274.5 ± 16.22^$	243.2 ± 10.32^$$$	273.5 ± 13.47^$
Plasma C-peptide (pmol/L); fasting 60 min post ipGTT	583 ± 80.47; 2274 ± 283.9	1954 ± 266.7; 4398 ± 298.6	1179 ± 91.03; 3167 ± 783.5^$$	1081 ± 68.94; 2479 ± 197.6^$$$	1163 ± 172.6; 2944 ± 334.7^$$
Insulin resistance (HOMA-IR)	1.43 ± 0.15	4.84 ± 0.63	2.87 ± 0.23^$$$	2.57 ± 0.15^$$$	2.87 ± 0.44^$$
Fasting plasma leptin (ng/mL)	13.23 ± 0.99	37.24 ± 5.39	15.88 ± 1.08^$$$	14.98 ± 1.99^$$$	27.48 ± 4.42^$
Plasma triglycerides (μmol/L)	805.2 ± 175.2	1523 ± 184.6	878 ± 199.7^$	565.1 ± 96.7^$$	1066 ± 282.6
Plasma adiponectin (ng/mL)	4184 ± 221	6005 ± 359	4439 ± 197^$$$	4893 ± 279^$$	5000 ± 134.8^$$
Plasma free fatty acids (FFA; μmol/L)	82.11 ± 10.64	234.4 ± 29.39	155.3 ± 14.12^$$	11.95 ± 4.13^$$$	55.27 ± 24.84^$$$
Plasma total cholesterol (mmol/L)	1.37 ± 0.12	2.21 ± 0.30	1.71 ± 0.25	1.58 ± 0.08^$	2.485 ± 0.19