Quercetin Prevents Diastolic Dysfunction Induced by a High-Cholesterol Diet: Role of Oxidative Stress and Bioenergetics in Hyperglycemic Rats

Figure 2

Quercetin protects against cardiac diastolic dysfunction induced by high-cholesterol diet. Ultrasound and Doppler imaging showing (a) A wave (atrial filling velocity) expressed as cm/seg and (b) E:A, expressed as the ratio of peak velocity of early to late filling of mitral inflow, in rats fed for 4 weeks with control diet (C), control diet containing 0.5% quercetin diet (CQ), high-cholesterol diet (HC), and high-cholesterol diet containing 0.5% quercetin (HCQ). Values are expressed as mean ± SEM. rats/group. Two-way ANOVA test and Bonferroni posttest. Statistical differences: , , and .

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