Genetic Code Expansion: A Powerful Tool for Understanding the Physiological Consequences of Oxidative Stress Protein Modifications

Figure 1

A variety of biological oxidants are capable of modifying susceptible amino acid sidechains to their Ox-PTM counterparts. The major groups of amino acids modified are the sulfur containing amino acids (cysteine and methionine) and the aromatic amino acids (tyrosine, tryptophan, and histidine).