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Figure 2: Molecular docking of flavonoids at the active site of Aden A2A (PDB: 3UZA), α-synuclein (PDB: 1XQ8), COMT (PDB: 1H1D), and MAO-B (PDB: 2C65). (a) Docking of flavonoids at the active site of Aden2A (green to epicatechin gallate, yellow to procyanidin, and blue to hesperidin). (b) Docking of flavonoids at the active site of α-synuclein (green to procyanidin, yellow to epicatechin gallate, and blue to rosinidin). (c) Docking of flavonoids at the COMT active site (green to epicatechin gallate and yellow to procyanidin and blue to europinidin) (ligand PDB). (d) Docking of flavonoids at the active site of MAO-B (green to hesperidin, yellow to epicatechin, and blue to aspalathin).