Computational Studies Applied to Flavonoids against Alzheimer’s and Parkinson’s Diseases

Table 2

Toxicity data, TPSA, and %ABS calculated on the Osiris tool for flavonoids.

Flavonoids	Toxicity risks	TPSA	%ABS
3-O-methylquercetin	No	116.450	68.824
8-prenylnaringenin	No	86.990	78.9884
Afzelechin	No	90.150	77.8982
Ampelopsin	No	147.680	58.050
Aromadendrin	No	107.220	72.009
Aspalathin	No	208.370	37.112
Aurantinidin	No	101.150	74.103
Butin	No	86.990	78.988
Capensinidin	No	88.380	78.508
Chrysin	No	66.760	85.967
Delphinidin	No	121.380	67.123
Di-hydrogossypetin	No	147.680	58.050
Di-hydromorin	No	127.450	65.029
Epicatechin	No	110.380	70.918
Eriodictyol	No	107.220	72.009
Europinidin	No	99.380	74.713
Fisetin	Mutagenic	107.220	72.009
Fisetinidol	No	90.150	77.898
Fustin	No	107.220	72.009
Epicatechin gallate	No	177.140	47.886
Genistein	Mutagenic/tumor/reproductive	86.990	78.988
Gossypetin	Mutagenic	147.680	58.050
Hesperidin	No	234.290	28.169
Hibiscetin	Mutagenic	167.910	51.071
Homoeriodictyol	No	96.220	75.804
Isosakuranetin	No	75.990	82.783
Luteolinidin	No	80.920	81.082
Meciadanol	No	99.380	74.713
Mesquitol	No	110.380	70.918
Morin	Mutagenic	127.450	65.029
Norartocarpetin	No	107.220	72.009
Pinocembrin	No	66.760	85.967
Procyanidin	Reproductive	331.140	−5.243
Rhamnetin	Mutagenic	116.450	68.824
Robinetinidol	No	110.380	70.918
Rosinidin	No	92.290	77.159
Sakuranetin	No	75.990	82.783
Sterubin	No	96.220	75.804
Taxifolin	No	127.450	65.029