Table 3: Description of energy scores of flavonoids and control compounds on PD target proteins.

FlavonoidsAden A2Aα-SynucleinCOMTMAO-B

3-O-methylquercetin−71.095−74.901−53.659−140.763
8-prenylnaringenin−83.692−83.012−67.998−145.425
Afzelechin−61.973−70.911−51.278−107.22
Ampelopsin−60.848−74.188−53.806−134.626
Aromadendrin−53.880−66.701−45.951−123.726
Aspalathin−55.009−86.361−56.396−150.386
Aurantinidin−67.749−75.414−56.591−117.977
Butin−68.355−77.949−60.034−124.25
Capensinidin−84.669−87.321−71.529−140.926
Chrysin−59.594−70.872−52.576−120.287
Delphinidin−70.457−82.877−68.376−126.481
Di-hydrogossypetin−56.359−73.612−48.949−135.483
Di-hydromorin−61.416−66.071−54.329−131.088
Epicatechin−66.996−74.661−53.054−122.78
Eriodictyol−66.790−74.167−55.545−119.801
Europinidin−75.421−79.694−74.993−140.585
Fisetin−67.182−79.763−64.252−130.773
Fisetinidol−64.279−72.271−59.406−118.506
Fustin−59.854−76.510−56.851−135.63
Epicatechin gallate−113.727−98.330−96.205−174.333
Genistein−68.316−73.585−58.867−119.162
Gossypetin−63.019−75.620−58.446−139.059
Hesperidin−101.446−89.698−65.656−181.222
Hibiscetin−71.879−75.302−60.718−137.019
Homoeriodictyol−75.599−82.786−62.698−141.639
Isosakuranetin−65.924−71.351−49.177−131.514
Luteolinidin−65.240−80.031−57.149−122.481
Meciadanol−73.596−77.668−55.342−126.337
Mesquitol−60.219−74.776−51.753−128.058
Morin−70.744−84.587−59.595−139.778
Norartocarpetin−67.527−77.898−60.514−137.774
Pinocembrin−56.707−66.573−46.254−113.423
Procyanidin−98.216−130.002−85.226−88.460
Rhamnetin−69.702−83.582−49.586−142.785
Robinetinidol−62.594−78.967−51.172−125.203
Rosinidin−83.735−95.587−63.376−149.196
Sakuranetin−70.695−74.984−51.408−129.56
Sterubin−69.560−77.022−56.015−141.623
Taxifolin−56.665−69.743−52.804−126.612