Black Seed Thymoquinone Improved Insulin Secretion, Hepatic Glycogen Storage, and Oxidative Stress in Streptozotocin-Induced Diabetic Male Wistar Rats

Table 4

The effect of NSO 2 mL/kg on mean pancreatic islet size (μm), insulin-positive islet area %, and insulin immunostaining intensity (integrated density) in STZ-induced diabetic rats.

Groups	Control	Nigella	Diabetic	Diabetic Nigella treated
Mean islet size (μm)	233.90 ± 24.71^a	247.52 ± 35.27^a	29.83.36 ± 83.17^b	170.61 ± 26.63^a
Insulin-positive islet area (%)	65.79 ± 9.81^a	68.52 ± 9.58^a	18.01 ± 3.42^c	43.05 ± 5.57^b
Insulin immunostaining intensity (integrated density)	92.50 ± 3.05^a	99.34 ± 2.23^a	60.93 ± 4.31^c	76.15 ± 1.92^b

Values are presented as mean ± SE. ^abcDifferent letters on numbers in each row represent a significant difference at .