Protective Effects of Taraxasterol against Ethanol-Induced Liver Injury by Regulating CYP2E1/Nrf2/HO-1 and NF-κB Signaling Pathways in Mice
Effects of taraxasterol on liver histopathology in mice with ethanol-induced liver injury (200x). The mice were treated with taraxasterol (2.5, 5, and 10 mg/kg, respectively) or TPN and induced with EtOH as described in Materials and Methods. The histopathological changes of liver tissues were observed under the optical microscope by H&E staining. (a) Normal group; (b) EtOH group; (c) TPN group; (d) 10 mg/kg of taraxasterol group; (e) 5 mg/kg of taraxasterol group; (f) 2.5 mg/kg of taraxasterol group.