Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection

Figure 1

Upregulation of eNOS and preserved total levels of NO metabolites in Nrf2 KO mice. (a) Representative Western blot of eNOS (upper panel) standardized to alpha-tubulin (lower panel) and densitometric analysis of eNOS expression in aorta and (b) heart of WT and Nrf2 KO mice detected by Western blot ( per group, means ± quartiles, , t-test). (c) Total NO species in different tissues of Nrf2 KO and WT mice ( per group, means ± SEM), (for statistical comparisons and SD please refer also to Table 2).

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